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Takashi Yaguchi

Position Associate Professor
Research Projects Management Unit of Microbiological Resources
Division Division of Bio-resources
TEL +81 43 226 2790
FAX +81 43 226 2486
E-mail yaguchi[at]



Main topics of research

Developing a system for preservation, management and distribution of pathogenic fungi and actinomycetes and adding new information

Main publications

  1. Motooka D, Fujimoto K, Tanaka R, Yaguchi T, Gotoh K, Maeda Y, Furuta Y, Kurakawa T, Goto N, Yasunaga T, Narazaki M, Kumanogoh A, Horii T, Iida T, Takeda K, Nakamura S: Fungal ITS1 deep-sequencing strategies to reconstruct the composition of a 26-species community and evaluation of the gut mycobiota of healthy Japanese individuals. Front Microbiol, doi: 10.3389/fmicb.2017.00238, 2017.
  2. Tetsuka N, Yaguchi Y, Machida H, Ito S, Miyairi I. Successful treatment of invasive pulmonary aspergillosis due to voriconazole-resistant Aspergillus lentulus with micafungin. Pediatrics Itn, in press.
  3. Imanishi Y, Tanaka R, Yaguchi T, Shimizu K. Capsule gene CAP64 is involved in the regulation of vacuole acidification in Cryptococcus neoformans. Mycoscience, 2016.
  4. Nakamura S, Sato H, Tanaka R, Yaguchi T. Verification of ribosomal proteins of Aspergillus fumigatus for the use of biomarkers in MALDI?TOF MS identification. Mass Spectrometry 5: A0049, 2016.
  5. Kuboi T, Okazaki K, Inotani M, Sugino M, Sadamura T, Nakano A, Kobayashi S, Ota A, Nishimura K, Yaguchi T. A case of cutaneous Paecilomyces formosus infection in an extremely premature infant. J Infect Chemother. 22: 339-341, 2016.
  6. Matsumoto T, NegishiT, Hamada M, Komaki H, Gonoi T, Yaguchi T. Nocardia shinanonensis sp. nov., isolated from a patient with endophthalmitis. Int J System Evol Microbiol, 66: 3324?3328, 2016.
  7. Nakayama M, Hosoya K, Shimizu-Imanishi Y, Chibana H, Yaguchi T. Development of rapid identification and risk analysis of Moniliella spp. in acidic processed foods. Biocont Sci, 21 (2): 73-80, 2016.
  8. Ogawa A, Matsumoto Y, Yaguchi T, Shimmura S, Tsubota K. Successful treatment of Beauveria bassiana fungal keratitis with topical voriconazole. J Infect Chemother, 22: 257-260, 2016.
  9. Saito T, Itabashi T, Wakana D, Takeda H, Yaguchi T, Kawai K, Hosoe T. Isolation and structure elucidation of new phthalide and phthalane derivatives, isolated as antimicrobial agents from Emericella sp. IFM 57991. J Antibiot; 69(2):89-96, 2016.
  10. Shigemura T, Nishina S, Nakazawa H, Matsuda K, Yaguchi T, Nakazawa Y. Early detection of Rhizopus DNA in the serum of a patient with rhino-orbital-cerebral mucormycosis following allogeneic hematopoietic stem cell transplantation. Int J Hematol. 103(3): 354-355, 2016.
  11. Suzuki R, Yikelamu A, Tanaka R, Igawa K, Yokozeki H, Yaguchi T. Studies in phylogeny, development of rapid identification, antifungal susceptibility and growth rates on clinical strains of Sporothrix schenckii complex in Japan. Med Mycol J. 57 (3): E47-E57, 2016.
  12. Fr?c M, Jezierska-Tys S, Yaguchi T. Occurrence, detection and molecular and metabolic characterization of heat-resistant fungi in soils and plants and their risk to human health. Advances in Agronomy. 132: 161-204, 2015.
  13. Matsuzawa T, Takaki GMC, Yaguchi T, Okada K, Abliz P, Gonoi T, Horie Y. Aspergillus arcoverdensis, a new species of Aspergillus section Fumigati isolated from caatinga soil in State of Pernambuco, Brazil. Mycoscience 56(2): 123?131, 2015.
  14. Tamiya H, Ochiai E, Kikuchi K, Yahiro M, Toyotome T, Watanabe A, Yaguchi T, Kamei K. Secondary metabolite profiles and antifungal drug susceptibility of Aspergillus fumigatus and closely related species, A. lentulus, A. udagawae, and A. viridinutans. J Infect Chemother 21(5): 385-91, 2015.
  15. Kusuya Y, Takahashi-Nakaguchi A, Takahashi H, Yaguchi T. Draft genome sequence of the pathogenic filamentous fungus Aspergillus udagawae strain IFM 46973T. Genome Announc ; 3(4). pii: e00834-15, 2015.
  16. Samson RA, Visagie CM, Houbraken J, Hong S-B, Hubka V, Klaassen CHW, Perrone G, Seifert KA, Susca A, Tanney JB, Varga J, Kocsube S, Szigeti G, Yaguchi T, Frisvad JC. Phylogeny, identification and nomenclature of the genus Aspergillus. Stud Mycology 78: 141-173, 2014.
  17. Visagie CM, Houbraken J, Frisvad JC, Hong S-B, Klaassen CHW, Perrone G, Seifert KA, Varga J, Yaguchi T, Samson RA. Identification and nomenclature of the genus Penicillium. Stud Mycology 78: 343-371, 2014.
  18. Hosoya K, Nakayama M, Tomiyama D, Matsuzawa T, Imanishi Y, Ueda S, Yaguchi T. Risk analysis and rapid detection of the genus Thermoascus, food spoilage fungi. Food Cont 41: 7-12, 2014.
  19. Matsuzawa T, Takaki GMC, Yaguchi T, Okada K, Gonoi T, Horie Y. Two new species of Aspergillus section Fumigati isolated from caatinga soil in the State of Pernambuco, Brazil. Mycoscience 55: 79-88, 2014.
  20. Matsuzawa T, Horie Y, Abliz P, Gonoi T, Yaguchi T. Aspergillus huiyaniae sp. nov., a teleomorphic species in sect. Fumigati isolated from desert soil in China. Mycoscience. 55: 213-220, 2014.
  21. Kikuchi K, Watanabe A, Ito J, Oku Y, Wuren T, Taguchi H, Yarita K, Muraosa Y, Yahiro M, Yaguchi T, Kamei K: Antifungal susceptibility of Aspergillus fumigatus clinical isolates collected from various areas in Japan. J Infect Chemother. 20: 336-338, 2014.
  22. Novakova A, Hubka V, Dudova Z, Matsuzawa T, Kubatova A, Yaguchi T, Kolarik M. New species in Aspergillus section Fumigati from reclamation sites in Wyoming (U.S.A.) and revision of A. viridinutans complex. Fungal Diversity 64: 253-274, 2014.
  23. Furusawa H, Miyazaki Y, Shiro Sonoda S, Tsuchiya K, Yaguchi T, Kamei K, Inase N. Penicilliosis marneffei complicated with interstitial pneumonia. Intern Med 53: 321-323, 2014.
  24. Hubka V, Peterson SW, Frisvad JC, Yaguchi T, Kubatova A, Kolarik M. Aspergillus waksmanii sp. nov. and Aspergillus marvanovae sp. nov., two closely related species in section Fumigati described using polyphasic approach. Int J Syst Evol Microbiol: 63: 783?789, 2013.
  25. Nakayama M, Hosoya K, Tomiyama D, Tsugukuni T, Matsuzawa T, Imanishi Y, Yaguchi T. Method for rapid detection and identification of Chaetomium and evaluation of resistance to peracetic acid. J Food Prot 76: 999-1005, 2013.
  26. Hosoya K, Nakayama M, Matsuzawa T, Imanishi Y, Hitomi J, Yaguchi T. Risk analysis and development of a rapid method for identifying four species of Byssochlamys. Food Control. 26:169-173, 2012.
  27. Yaguchi T, Imanishi Y, Matsuzawa T, Hosoya K, Hitomi J, Nakayama M. Method for identifying heat-resistant fungi of the genus Neosartorya. J Food Prot 75:1806-1813, 2012.
  28. Hosoe T, Mori N, Kamano K, Itabashi T, Yaguchi T, Kawai K. A new antifungal yellow pigment from Aspergillus nishimurae. J Antibiot 64: 211-212, 2011.
  29. Kimura M, Yaguchi T, Sutton DA, Fothergill AW, Thompson EH, Wickes BL Disseminated human conidiobolomycosis due to Conidiobolus lamprauges. J Clin Microbiol 49:752-756, 2011.
  30. Nakayama M, Hosoya K, Matsuzawa T, Hiro Y, Sako A, Tokuda H, Yaguchi T. Rapid method for identifying Byssochlamys and Hamigera. J Food Prot. 73: 1486?1492, 2010.
  31. Yaguchi T, Matsuzawa T, Tanaka R, Abliz P, Hui Y, Horie Y: Two new species of Neosartorya isolated from soil in Xinjiang, China. Mycoscience 51: 253-262, 2010.
  32. Wakana D, Hosoe T, Wachi H, Itabashi T, Fukushima K, Yaguchi T, Kawai K: The cytotoxic and antfungal activities of two new sesquiterpenes, malfilanol A and B, derived from Malbranchea filamentosa. J Antibiotics 62: 217-219, 2009.
  33. Nakadate S, Nozawa K, Sato H, Horie H, Fujii Y, Nagai M, Hosoe T, Kawai K, Yaguchi T, Fukushima K:An Antifungal Cyclic Depsipeptide, Eujavanicin A, Isolated from Eupenicillium javanicum. J Natural Products 71: 1640-1642, 2008.
  34. Balajee SA, Houbraken J, Verweij PE, Hong S-H, Yaguchi T, Varga J, Samson RA: Aspergillus Species Identification in the Clinical Setting. Studies in Mycology 59: 39-46, 2007.
  35. Kushida N, Watanabe N, Okuda T, Yokoyama F, Gyobu Y, Yaguchi T: PF1270A, B and C, Novel Histamine H3 Receptor Ligands Produced by Penicillium waksmanii PF1270. J Antibiot 60: 667-673, 2007.
  36. Yaguchi T, Tanaka R, Nishimura K, Udagawa S: Molecular phylogenetics of strains morphologically identified as Fonsecaea pedrosoi from clinical specimens. Mycoses 49: 255-260, 2007.
  37. Yaguchi T, Horie H, Tanaka R, Matsuzawa T, Ito J, Nishimura K: Molecular phylogenetics of multiple genes on Aspergillus section Fumigati isolated from clinical specimens in Japan. J Med Mycol 48:37-46, 2007.
  38. Yaguchi T, Udagawa S, Nishimura K: Geosmithia argillacea is the anamorph of Talaromyces eburneus as a heat resistant fungus. Cryptogamie, Mycologie 26: 133-141, 2005.
  39. Okamoto S, Hosoe T, Itabashi T, Nozawa K, Okada K, Takaki GC, Chikamori M, Yaguchi T, Fukushima K, Miyaji M, Kawai K: New decalin derivative, eujavanoic acids A and B, from Eupenicillium javanicum. J Natural Products 67: 1580-1583, 2004.
  40. Kuriyama T, Kakemoto E, Takahashi N, Imamura K, Oyama K, Suzuki E, Harimaya K, Yaguchi T, Ozoe Y: Receptor assay-guided isolation of anti-GABAergic insecticidal alkaloids from a fungal culture. J Agricultural Food Chemistry 52: 3884-3887, 2004.